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Submitted: 14 Apr 2010
Accepted: 14 Aug 2010
ePublished: 30 Jun 2011
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Avicenna J Dent Res. 2011;3(1): 1-11.
  Abstract View: 961
  PDF Download: 682

Review Article

Oxidative Stress and Antioxidants

F Ahmadi Motamayel 1*

1 Assistant Professor of Oral Medicine, Dental Research Center, Faculty of Dentistry – Hamadan University of Medical Sciences, Hamadan, Iran.
*Corresponding Author: Corresponding Author: F. Ahmadi Motamayel– Address: Hamadan dental school- department of Oral Medicine – Tel: 09188130684, Email: Ahmadimotemayel@umsha.ac.ir

Abstract

The first reaction between food components and biological tissues occurs in the oral cavity. Saliva modulates the ecosystem in the oral cavity and plays a critical role in oral homeostasis. In addition, saliva is a first line of defense against free radical-mediated stress. Salivary antioxidant defense mechanisms seem to be very important. In this study we discuss in detail free radicals (FR) and reactive oxygen species, oxidative stress, oxidative stress and disease, antioxidants, factors influencing antioxidant efficacy and level, antioxidants and disease prevention, antioxidants and disease treatment, classification system and finally salivary antioxidants. 
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