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Submitted: 16 Apr 2022
Accepted: 06 Feb 2024
ePublished: 29 Mar 2024
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Avicenna J Dent Res. 2024;16(1): 46-56.
doi: 10.34172/ajdr.1607

Scopus ID: 85200665108
  Abstract View: 295
  PDF Download: 191

Review Article

Utilizing Saliva Biomarkers for Diagnostic Purposes

Fatemeh Ahmadi -Motamayel 1 ORCID logo, Ali Mahdavinezhad 2 ORCID logo, Seyedeh Sareh Hendi 3* ORCID logo

1 Dental Research Center, Hamadan University of Medical Sciences, Hamadan, Iran
2 Department of Genetics and Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
3 Department of Endodontics, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
*Corresponding Author: Seyedeh Sareh Hendi, Email: hendispx@yahoo.com

Abstract

Saliva, as a complex fluid composed of secretory products from salivary glands, plays different roles in the oral cavity. Saliva has potentially been used for the diagnosis of viral, bacterial, and systemic diseases in the last few years. Individuals with minimal training can collect saliva as a diagnostic fluid easily and non-invasively. Saliva is a simple and economical method for screening the public. However, saliva has various levels of variability and instability. A systematic search of published literature was performed on Medline using PubMed. Several keywords, including saliva, systemic disease, disease, health, and diagnosis, were used in this search. This review discusses the diagnostic potential of salivary systemic diseases such as infectious, malignant, and other systemic diseases.

Please cite this article as follows: Ahmadi Motamayel F, Mahdavinezhad A, Hendi SS. Utilizing saliva biomarkers for diagnostic purposes. Avicenna J Dent Res. 2024; 16(1):46-56. doi:10.34172/ajdr.1607
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