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Submitted: 11 Nov 2014
Revision: 19 May 2015
Accepted: 15 Jun 2015
ePublished: 04 Jul 2016
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Avicenna J Dent Res. 2016;8(3): 4.
doi: 10.17795/ajdr-25275
  Abstract View: 1338
  PDF Download: 546

Research Article

How Useful is the AgNOR Staining Method for the Diagnosis of Salivary Gland Tumors?

Soussan Irani 1*, Farahnaz Bidari Zerehpoush 2, Shahram Sabeti 2

1 Associate Professor, Dental Research Center, Department of Oral Pathology, Dental Faculty, Hamadan University of Medical Sciences, Hamadan, IR Iran
2 Assistant Professor, Pathology Department, Loghman Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
*Corresponding Author: * Corresponding author: Soussan Irani, Associate Professor, Dental Research Center, Department of Oral Pathology, Dental Faculty, Hamadan University of Medical Sciences, Hamadan, IR Iran. Tel: +98-8118354250, Fax: +98-8118354220, E-mail: , Email: sousanirani@gmail.com

Abstract

Objectives: The purpose of this study was to determine the numbers and mean areas of the AgNOR dots in the 3 most common salivary gland tumors.

Materials and Methods: One hundred and seventy paraffin blocks histologically diagnosed as pleomorphic adenoma, adenoid cystic carcinoma, and mucoepidermoid carcinoma were selected from the archives of the pathology department of Loghman hospital, Tehran, Iran and then cut and stained using the standard AgNOR method. The number and area of AgNOR dots were evaluated. Chi-square and Pearson correlation (2-tailed) tests were used for statistical analysis. The significance level was P < 0.05.

Results: The chi-square test showed significant differences between tumor types and the numbers of AgNORs (P = 0.000) and between tumor types and areas of AgNORs (P = 0.000).

Conclusions: The AgNOR technique can be used to diagnose salivary gland tumors. 


 
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Abstract View: 1339

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