Hamadan University of Medical Sciences Avicenna Journal of Dental Research 2423-7582 13 1 2021 03 30 Dental Management of Peripheral Giant Cell Granuloma in an 8-Year-Old Boy: A Case Report 38 41 10.34172/ajdr.2021.07 EN Arghavan Kamali Sabeti Niloofar Entezari Moghaddam Fariba Naderi Journal Article 10.34172/ajdr.2021.07 2020 12 28 2021 02 23 Peripheral giant cell granuloma (PGCG) or the so-called giant cell epulis is the most common oral giant cell lesion. It normally appears as a soft tissue purple-red nodule. This lesion is certainly not a true neoplasm, but in nature, it may be reactive, thought to be stimulated by local irritation or trauma. Nonetheless, the exact cause is definitely not understood well. In appearance, lesions vary from smooth, uniformly outlined masses to irregularly developed, multilobed surface indentation protuberances. Margin ulcerations are occasionally observed as well. The lesions are painless, differ in size, and can cover many teeth. It may be a lesion on the gingiva or alveolar crest that is sessile or pedunculated, common with respect to the molars and incisors and occurs in reaction to the local response.