Hamadan University of Medical Sciences Avicenna Journal of Dental Research 2423-7582 2 1 2010 12 30 Squamous Cell Carcinoma arising in Oral Lichen Planus 82 85 EN S Irani Journal Article It has been argued that Oral Lichen Planus (OLP) may increase the risk of oral cancer. Patients with OLP may be at an increased risk for developing of OSCC (Oral Squamous Cell Carcinoma). Here, the author reports a case of OLP initially presenting with a clearly benign OLP lesion that transformed into OSCC over a course of 18 months. This report may provide a clear evidence for OLP lesion as a potential pre-malignant state.