Hamadan University of Medical Sciences Avicenna Journal of Dental Research 2423-7582 14 2 2022 06 28 Assessment of Frontal Sinus Morphology and Cervical Vertebral Maturation for Evaluation of Skeletal Maturity 69 73 10.34172/ajdr.2022.13 EN Sanjay Prasad Gupta https://orcid.org/0000-0002-2510-5699 Samarika Dahal https://orcid.org/0000-0001-8512-0850 Shristi Rauniyar https://orcid.org/0000-0001-7244-1487 Journal Article 10.34172/ajdr.2022.13 2022 01 24 2022 02 22 Background: The growth prediction using reliable growth assessment methods is an invaluable tool during orthodontic treatment planning. This study aimed to examine the relationship between frontal sinus (FS) morphology and cervical vertebral maturation (CVM) to predict the skeletal maturity of an individual. Methods: The present study consisted of 252 lateral cephalograms of orthodontic patients. CVM stages and FS parameters such as FS height, FS width, and FS index were assessed using the same lateral cephalogram. Statistical methods including t test, analysis of variance (ANOVA), and Pearson correlation (r) were used for the statistical analysis. Results: FS height and width were greater in males (24.33±4.21; 10.08±3.20) compared to females (21.43±5.34; 8.12±2.19), indicating a statistical difference (P<0.05). However, FS index did not show a statistically significant difference (P=0.32) between males (2.59±0.74) and females (2.69±0.44) . FS height and width increased significantly in a linear fashion from CVM stage 1 to stage 6. FS index, on the other hand, did not exhibit any statistically significant differences among CVM stages in both males and females. FS height and width showed a significant weak to moderate correlation with CVM stages in both males and females. However, FS index exhibited a mild and weak negative correlation with the CVM stages in both males and females. Conclusions: FS height and width had a significant weak to moderate correlation with CVM stages in both the males and females, while FS index had a weak negative correlation with CVM stages in both males and females. Unlike the CVM method, the FS morphology cannot be reliably utilized to assess the skeletal maturity.