Morad Hedayati Panah
1 
, Leila Shahsavand Baghdadi
1, Saeedeh Fatholahi
1* 1 Department of Periodontics, School of Dentistry, Ilam University of Medical Sciences, Ilam, Iran
Abstract
Aplastic anemia (AA) is a rare disease characterized by pancytopenia, susceptibility to infection, and difficulty maintaining hemostasis. Drugs are considered to be one of the most important risk factors associated with AA. Various studies have identified the pharmaceutical agents that may contribute to the development of AA. It is common for patients with severe periodontal disease and AA to experience spontaneous bleeding during brushing in terms of thrombocytopenia, which may further exacerbate dental problems. AA patients require comprehensive periodontal treatment that necessitates collaboration with a hematologist.